OCT can detect subtle anatomical changes in the organ of Corti during the course of post-natal cochlear development.
OCT produces images of sufficient resolution to allow quantitative measurements of morphology in intra-cochlear soft tissues relevant to hearing in Tecta Transgenic mice.
OCT can provide relevant structural information that is difficult to obtain with conventional histology.
Additional technical information:
Quantitative imaging of cochlear soft tissues in wild-type and hearing-impaired transgenic mice by spectral domain optical coherence tomography
OCT (left) and tissue samples (right)
of the detailed structure of the ear